Претрага
85 items
-
Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach
Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach" in Pharmaceutics, MDPI, Basel, Switzerland (2021). https://doi.org/10.3390/pharmaceutics13081188
-
Microstructure refinement and physical properties of Ag-SnO2 based contact materials prepared by high-energy ball milling
Ćosović Vladan, Pavlović Mila, Ćosović Aleksandar, Vulić Predrag, Premović Milena, Živković Dragana, Talijan Nadežda (2013)Ćosović Vladan, Pavlović Mila, Ćosović Aleksandar, Vulić Predrag, Premović Milena, Živković Dragana, Talijan Nadežda. "Microstructure refinement and physical properties of Ag-SnO2 based contact materials prepared by high-energy ball milling" in Science of Sintering 45, Belgrade:Yugoslav Committee for ETAN (2013): 173-180. https://doi.org/10.2298/SOS1302173C
-
Chalcopyrite Floatability in Flotation Plant of the Rudnik Mine
У раду је приказан део резултата обимних индустријских испитивања утицаја финоће млевења руде на резултате флотације минерала олова, бакра и цинка из руде рудника "Рудник". На основу резултата индустријских испитивања, констатовано је да се при једностепеном млевењу и двостепеном класирању комплексне Pb-Zn-Cu руде, појављује проблем тзв. диференцијалне мељивости. Наиме, галенит као мек минерал знатно брже се уситњава од осталих минерала у руди. Ово доводи до тога да минерал галенит прелази у ситне класе које споро флотају, а у ...Predrag Lazić, Đurica Nikšić, Rudolf Tomanec, Dušica Vučinić, Lidija Cvetićanin. "Chalcopyrite Floatability in Flotation Plant of the Rudnik Mine" in Journal of Mining Science, Pleiades Publishing Ltd (2020). https://doi.org/10.1134/S1062739120016552
-
Synthesis and characterization of high-pressure and high-temperature sphene (CaTiSiO5)
Jelena Pantić, Vladimir Urbanovich, Vesna Poharc-Logar, Bojan Jokić, Marija Stojmenović, Aleksandar Kremenović, Branko Matović (2014)Sphene (CaTiSiO5), a calcium titanosilicate ceramic has been prepared from a powder mixture of CaCO3, TiO2 and SiO2 using vibro-milling for homogenization and activation of precursors. During the highpressure and high-temperature synthesis (HPS) process at 4 GPa and 1,200 °C, sphene undergoes into phase transition, from room-temperature phase P21/a to high-temperature phase A2/a. Evidence of that structural phase transition is given in this paper using infrared, Raman spectroscopy and X-ray powder diffraction. Rietveld refinement was employed to get the ...Jelena Pantić, Vladimir Urbanovich, Vesna Poharc-Logar, Bojan Jokić, Marija Stojmenović, Aleksandar Kremenović, Branko Matović. "Synthesis and characterization of high-pressure and high-temperature sphene (CaTiSiO5)" in Physics and Chemistry of Minerals, Springer Science and Business Media LLC (2014). https://doi.org/10.1007/s00269-014-0693-x
-
Curcumin nanonization using an alternative small-scale production unit: selection of proper stabilizer applying basic physicochemical consideration and biological activity assessment of nanocrystals
Ines Nikolić, Jelena Antić-Stanković, Dragana Božić, Danijela Ranđelović, Bojan Marković, Dominique Jasmin Lunter, Aleksandar Kremenović, Miroslav Savić, Snežana Savić (2020)As the number of poorly soluble drugs is increasing, nanocrystals have become very interesting due to wide range of application possibilities. Curcumin was used as a model active ingredient in this work. Even though it has many proven positive effects, due to its physicochemical issues, its possibilities have not been fully exploited. The goal of this work was to select optimal conditions for a top-down method for curcumin nanosuspension production, and to perform their comprehensive characterization applying complementary methodologies: ...Ines Nikolić, Jelena Antić-Stanković, Dragana Božić, Danijela Ranđelović, Bojan Marković, Dominique Jasmin Lunter, Aleksandar Kremenović, Miroslav Savić, Snežana Savić. "Curcumin nanonization using an alternative small-scale production unit: selection of proper stabilizer applying basic physicochemical consideration and biological activity assessment of nanocrystals" in Review on advanced materials science, Walter de Gruyter GmbH (2020). https://doi.org/10.1515/rams-2020-0043
-
Microemulsion with aromatic oil as cleaner media for electropolymerisation
Abstract Microemulsion polymerization is widely used as a cleaner alternative way to prepare intrinsically conductive polymers. We studied isothermal phase diagrams for microemulsions of the electropolymerizable heterocyclic aromatic oil 3,4-ethylenedioxythiophene (EDOT), aqueous LiClO4 solution and alkyl polyethoxylate. Our specific goal was to assess the effect of LiClO4 salt on the phase behaviour. The phase behaviour was characterized by stepwise titration and microscopic analyses. Here we found that the increase of the concentration of LiClO4 salt shifts the microemulsion region ...M. Ilić, F.-H. Haegel, S. Zlatanovic, N. Potkonjak, B. Simonovic. "Microemulsion with aromatic oil as cleaner media for electropolymerisation" in Environmental Chemistry Letters, Springer Science and Business Media LLC (2005). https://doi.org/10.1007/s10311-005-0101-3
-
Determination of parameters for wet grinding of phosphates in a laboratory ball mill and classification in a hydrocyclone
Компанија Elixir Прахово у свом производном процесу користи суво млевење сировог фосфата за своју производњу. Међутим, због повећане влаге у сировом фосфату која изазива потешкоће у фази сувог млевења, разматра се могућност увођења мокрог млевења у индустријском постројењу у Прахову. Влага улазног сировог фосфата варира од барже до барже, и креће се у границама 5-10% H2O, што је јако високо за процес сувог млевења а ствара одређене проблеме и на транспортном систему (систем редлерских транспортери). За сагледавање могућности мокрог млевења ...Predrag Lazić, Đurica Nikšić, Vladan Živković, Nemanja Todorović. "Determination of parameters for wet grinding of phosphates in a laboratory ball mill and classification in a hydrocyclone" in Podzemni radovi, Centre for Evaluation in Education and Science (CEON/CEES) (2024). https://doi.org/10.5937/podrad2444019L
-
On the Dirichlet divisor problem in short intervals
Ivić Aleksandar, Zhai Wenguang (2014)Ivić Aleksandar, Zhai Wenguang. "On the Dirichlet divisor problem in short intervals" in The Ramanujan Journal no. 33, New York, USA:Springer Science+Business Media (2014): 447-465. https://doi.org/10.1007/s11139-013-9470-6
-
Threshold-induced correlations in the Random Field Ising Model
Sanja Janićević, Dragutin Jovković, Lasse Laurson, Đorđe Spasojević. "Threshold-induced correlations in the Random Field Ising Model" in Scientific Reports, Springer Science and Business Media LLC (2018). https://doi.org/10.1038/s41598-018-20759-6
-
Introductory editorial - Special issue: Genesis and protection of groundwater in carbonate aquifer
Saša Milanović (2019)Saša Milanović. "Introductory editorial - Special issue: Genesis and protection of groundwater in carbonate aquifer" in Carbonates and Evaporites, Springer Science and Business Media LLC (2019). https://doi.org/10.1007/s13146-019-00487-2
-
Mean-based iterative methods for finding multiple roots in nonlinear chemistry problems
Dejan Ćebić, Nebojša M. Ralević (2021)Dejan Ćebić, Nebojša M. Ralević. "Mean-based iterative methods for finding multiple roots in nonlinear chemistry problems" in Journal of Mathematical Chemistry, Springer Science and Business Media LLC (2021). https://doi.org/10.1007/s10910-021-01253-3
-
An efficient class of optimal sixteenth-order root-finding methods and their basins of attraction
Dejan Ćebić, Nebojša M. Ralević (2022)Dejan Ćebić, Nebojša M. Ralević. "An efficient class of optimal sixteenth-order root-finding methods and their basins of attraction" in Journal of Mathematical Chemistry, Springer Science and Business Media LLC (2022). https://doi.org/10.1007/s10910-022-01371-6
-
Characterization of bituminite in Kimmeridge Clay by confocal laser scanning and atomic force microscopy
Paul C. Hackley, Jolanta Kus, João Graciano Mendonça Filho, Andrew D. Czaja, Angeles G. Borrego, Dragana Životić, Brett J. Valentine, Javin J. Hatcheries (2022)This work investigates bituminite (amorphous sedimentary organic matter) in Upper Jurassic Kimmeridge Clay source rock via confocal laser scanning microscopy (CLSM) and atomic force microscopy (AFM). These petrographic tools were used to provide better understanding of the nature of bituminite, which has been historically difficult to identify and differentiate from similar organic matter types in source rocks. As part of an International Committee for Coal and Organic Petrology (ICCP) working group, an immature (0.42% vitrinite reflectance), organic-rich (44.1 wt% ...Битуминит, Kонфокална ласерска скенирајућа микроскопија, Mикроскопија атомских сила, Органска петрологија, Термичка зрелостPaul C. Hackley, Jolanta Kus, João Graciano Mendonça Filho, Andrew D. Czaja, Angeles G. Borrego, Dragana Životić, Brett J. Valentine, Javin J. Hatcheries. "Characterization of bituminite in Kimmeridge Clay by confocal laser scanning and atomic force microscopy" in International Journal of Coal Geology, Elsevier BV (2022). https://doi.org/10.1016/j.coal.2022.103927
-
A hydraulic–hydrochemical approach to impact assessment of a grout curtain on karst aquifer behavior
Igor Jemcov, Marina Ćuk Đurović (2020)Igor Jemcov, Marina Ćuk Đurović. "A hydraulic–hydrochemical approach to impact assessment of a grout curtain on karst aquifer behavior" in Hydrogeology Journal, Springer Science and Business Media LLC (2020). https://doi.org/10.1007/s10040-020-02245-4
-
Intrinsic groundwater vulnerability assessment by multiparameter methods, a case study of Suva Planina Mountain (SE Serbia)
Branislav Petrović (2020)Branislav Petrović. "Intrinsic groundwater vulnerability assessment by multiparameter methods, a case study of Suva Planina Mountain (SE Serbia)" in Environmental Earth Sciences, Springer Science and Business Media LLC (2020). https://doi.org/10.1007/s12665-020-8825-8
-
Alpine thermal events in the central Serbo-Macedonian Massif (southeastern Serbia)
Milorad D. Antić, Alexandre Kounov, Branislav Trivić, Andreas Wetzel, Irena Peytcheva, Albrecht von Quadt (2015)Milorad D. Antić, Alexandre Kounov, Branislav Trivić, Andreas Wetzel, Irena Peytcheva, Albrecht von Quadt. "Alpine thermal events in the central Serbo-Macedonian Massif (southeastern Serbia)" in International Journal of Earth Sciences, Springer Science and Business Media LLC (2015). https://doi.org/10.1007/s00531-015-1266-z
-
Review: Methodological approaches and research techniques for addressing construction and remediation problems in karst reservoirs
Saša Milanović, Ljiljana Vasić (2021)Saša Milanović, Ljiljana Vasić. "Review: Methodological approaches and research techniques for addressing construction and remediation problems in karst reservoirs" in Hydrogeology Journal, Springer Science and Business Media LLC (2021). https://doi.org/10.1007/s10040-020-02280-1
-
Hydrochemical changes and groundwater grouping data by multivariate statistical methods within one karst system: recharge–discharge zone (Eastern Serbia case study)
Ljiljana Vasić, Dragana Živojinović, Vladana Rajaković-Ognjanović. "Hydrochemical changes and groundwater grouping data by multivariate statistical methods within one karst system: recharge–discharge zone (Eastern Serbia case study)" in Carbonates and Evaporites, Springer Science and Business Media LLC (2020). https://doi.org/10.1007/s13146-019-00548-6
-
Flood protection and water utilization of karst poljes: example of Gatačko Polje, Eastern Herzegovina
Tina Dašić, Ljiljana Vasić (2020)Earth-Surface Processes,Geology, Pollution, Soil Science, Water Science and Technology, Environmental Chemistry,Global and Planetary ChangeTina Dašić, Ljiljana Vasić. "Flood protection and water utilization of karst poljes: example of Gatačko Polje, Eastern Herzegovina" in Environmental Earth Sciences, Springer Science and Business Media LLC (2020). https://doi.org/10.1007/s12665-020-08987-4
-
Otoliths in situ from Sarmatian (Middle Miocene) fishes of the Paratethys. Part IV: Scorpaenidae, Labridae, and Gobiesocidae
Werner Schwarzhans, Giorgio Carnevale, Sanja Japundžić, Katarina Bradić-Milinović. "Otoliths in situ from Sarmatian (Middle Miocene) fishes of the Paratethys. Part IV: Scorpaenidae, Labridae, and Gobiesocidae" in Swiss Journal of Palaeontology, Springer Science and Business Media LLC (2017). https://doi.org/10.1007/s13358-017-0124-y