Претрага

Упит dcterms_creator_txt:Vulic Predrag J

1023 items

  • Alpine thermal events in the central Serbo-Macedonian Massif (southeastern Serbia)

    Milorad D. Antić, Alexandre Kounov, Branislav Trivić, Andreas Wetzel, Irena Peytcheva, Albrecht von Quadt (2015)
    General Earth and Planetary Sciences

  • Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study

    Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)
    Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...
    Pharmaceutical Science
    ... • ++ || |- 90 250 *** [ F-0.4 | 80 | + H || *** f |- 70 200 -| . + * | —~ -03 L —~ E J • • ii 60 E\Ž =aso J · | Olsa& Ć " |EE:7 o | š F-0.2 L40 M 00 J · š " } LJ LI | [3 50 | -0.1 L20 J F | 10 01—+—0 7 Tr—_r— SIM | SIM SIM IM 00 Lo sucrose/mannitol before M M + +I + + ion: 2+1 ...
    ... T__= 153.27 *C peak s -48 AH = 162.09 J/g - o i-] o -9 -0.66 = [} —-1.32 > < > -1.98 Š | T_= 154.03 *C % -2.64 |- AH = 77.71 J/g _ šl:) | ii L ii L ii L | L L ı| 0.0 | iii -2.6 -- - -5.2 | J T__= 189.87 *C | peak 8L AH = 126.15 J/g | . L || - l L || L : ıj 0 50 100 150 ...
    ... intravenous nanosuspensions. Int. J. Pharm. 586, 119555 https://doi.org/10.1016/j. ijpharm.2020.119555. Patel, S.M., Nail, S.L., Pikal, M.J., Geidobler, R., Winter, G., Hawe, A., Davagnino, J., Gupta, S.R., 2017. Lyophilized drug product cake appearance: what is acceptable? J. Pharm. Sci. 106 (7), 1706–1721 ...

  • The influence of alkyl polyglucosides (and highly ethoxylated alcohol boosters) on the phase behavior of a water/toluene/technical alkyl polyethoxylate microemulsion system

    Marija Ilic, Franz-Hubert Haegel, Vesna Pavelkic, Dragan Zlatanovic, Snezana Nikolic-Mandic, Aleksandar Lolic, Zoran Nedic (2016)
    The influence of additives (alkyl polyglucoside, Glucopon 600 CS UP and alcohol ethoxylate C18E100) on the behavior of the water/toluene/Lutensol ON 50 (technical oxoalcohol, i-C10E5) microemulsion system as a function of temperature and composition has been investigated. The phase behavior of the microemulsions was determined by vertical sections through the Gibbs phase prism (fish-like phase diagrams). Alkyl polyglucoside shifts the one phase region to lower temperatures compared with water/toluene/Lutensol ON 50 mixtures. This is contrary to the expectation, considering ...
    микроемулзија, толуен, алкил полиглукозид, оксоалкохол етоксилат, појачивач ефикасности, „fish“ дијаграми
    ... Mihailescu, M. Monkenbusch, H. Endo, J. Allgaier, G. Gompper, J. Stellbrink, D. Richter, B. Jakobs, T. Sott- manmn, B. Farago, J. Chem. Phys. 115 (2001) 9563-9577 A. Kabalnov, U. Olsson, H. Wennerstrom, Langmuir 10 (1994) 2159-2169 C. Frank, H. Frielinghaus, J. Allgaier, D. Richter, Lang- muir ...
    ... Amsterdam, 2001, pp. 39-44 H. Endo, M. Mihailescu, M. Monkenbusch, J. Allgaier, G. Gompper, D. Richter, B. Jakobs, T. Sottmann, R. Strey, l. Grillo, J. Chem. Phys. 115 (2001) 580-600 B. Jakobs, T. Sottmann, R. Strey, J. Allgaier, L. Willner, D. Richter, Langmuir 15 (1999) 6707-6711 T. Sottmann ...
    ... 1245-1248 A. Stradner, B. Mayer, T. Sottmann, A. Hermetter, O. Glatter, J. Phys. Chem., B 103 (1999) 6680-6689 I.F. Uchegbu, S.P. Vyas, Int. J. Pharm. 172 (1998) 33-70 R. Schwering, D. Ghosh, R. Strey, T. Sottmann, J. Chem. Eng. Data 60 (2015) 124-136 K. Hill, W. von Rybinski, G. Stoll, Alky ...

  • Composition of organic matter and thermal maturity of Mesozoic and Cenozoic sedimentary rocks in East Herzegovina (External Dinarides, Bosnia and Herzegovina)

    Nikoleta Aleksić, Aleksandar Kostić, Miloš Radonjić (2021)
    This paper presents the first data on the organic matter and thermal maturity of Mesozoic and Cenozoic sedimentary rocks in the East Herzegovina region of the External Dinarides. Representative, organic-rich samples from outcropping sedimentary rocks of different ages in the area (Triassic to Neogene) were selected and analysed. The organic matter was studied by Rock-Eval pyrolysis and under the microscope in reflected non-polarized light and incident blue light. The results obtained show the presence of different types of organic ...
    nafta i gas, Rock-Eval, refleksija vitrinita, maceral, termička zrelost
    ... Bouzinos, A., Cardott, J. B., Cook, C. A., Eble, C., Flores, D., Gentzis, T., Goncalves, P. A., Filho Mendoca, G. J., Hamor-Vido, M., Jelonek, I., Kommeren, K., Knowles, W., Kus, J., Mastalerz, M., Menezes, R. T., Newman, J., Oikonomopoulos, K. I., Pawlewicz, M., Pickel, W., Potter, J., Ranasinghe, P ...
    ... Gentzis, T., Goncalves, P. A., Filho Mendoca, G. J., Hamor-Vido, M., Jelonek, I., Kommeren, K., Knowles, W., Kus, J., Mastalerz, M., Menezes, R. T., Newman, J., Oikonomopoulos, K. I., Pawlewicz, M., Pickel, W., Potter, J., Ranasinghe, P, Read, H., Reyes, J., De La Rosa Rodriguez, G., Viegas Alves Fernandes ...
    ... Espitalié, J., Deroo, G. & Marquis, F., 1985. La pyrolyse Rock-Eval et ses applications. Deuxième partie. Oil & Gas Science and Technology. L’Institut Français du Pétrole Energies Nouvelles, 40: 755–784. Espitalié, J., Laporte, J. L., Madec, M., Marquis, F., Leplat, P., Poulet, J. & Boutefeu, ...

  • Adsorption and degradation of some psychiatric drugs by sol-gel synthesized titania-based photocatalysts: influence of tungsten and sodium content

    Nina L. Finčur, Maja J. Šćepanović, Mirjana Grujić-Brojčin, Biljana F. Abramović, Jugoslav B. Krstić, Aleksandar Kremenović, Tatjana Srećković, Aleksandar Golubović (2019)
    Mesoporous anatase nanopowders were doped with 0.05−0.5 mol% of W6, in order to obtain more efficient photocatalyst than TiO2 Degussa P25 in the degradation of amitriptyline (AMI) under simulated solar irradiation (SSI). Dominant XRPD peaks were ascribed to anatase phase, with additional peaks which could correspond to brookite, TiO2 bronze and sodium titanate, Na2Ti9O19. The Raman scattering measurements have confirmed anatase as dominant phase, with broad Raman feature at ~270 cm−1 possibly related to Ti–O–Na stretching vibration. All W-doped ...
    Sol-gel synthesis, Doped titania nanopowders, XRPD, Raman spectroscopy, Adsorption and photocatalytic degradation, Psychiatric drugs

  • Model of the Geomagnetic reference field of the Republic of Serbia

    Spomenko J. Mihajlović, Vesna Cvetkov (2024)

  • Mean-based iterative methods for finding multiple roots in nonlinear chemistry problems

    Dejan Ćebić, Nebojša M. Ralević (2021)
    нелинеарне једначине, поступци засновани на срединама, вишеструки корени,

  • Long-term planning methodology for improving wood biomass utilization

    Vladimir Vukašinović, Dušan Gordić, Marija Živković, Davor Koncalović, Dubravka Živković (2019)
    The insufficiently developed forest management system is often followed by undeveloped forest resources supply chain and insufficient institutional support. These cause inefficient usage of fuel-wood as well as huge amounts of unused forest residues. In order to achieve optimal and long-term sustainable utilisation of biomass, an original methodology based on the interaction of mathematical optimization and backcasting approach has been developed. Mathematical optimization is used for both generation and consideration of techno-economic parameters of the forest biomass supply chain. ...
    Long-term planning methodology, Forest biomass, MINLP, Backcasting

  • Evidence of Variscan and Alpine tectonics in the structural and thermochronological record of the central Serbo-Macedonian Massif (south-eastern Serbia)

    Milorad D. Antić, Alexandre Kounov, Branislav Trivić, Richard Spikings, Andreas Wetzel (2016)
    General Earth and Planetary Sciences
    ... Burg J-P (1987) Regional shear variation in relation to dia- pirislm and · folding. J · Struct Geol 9:025—934. doi:10.1016/0191-8141(87)90002-2 Burg J-P (2012) Rhodope: from Mesozoic convergence to Cenozoic extension. Review of petro-structural data in the geochronologi- cal frame. J Virtual ...
    ... Tectonics 29:TC2002. doi:10.1029/2000TC002509 Kounov A, Burg J-P, Bernoulli D et al (2011) Paleostress analysis of Cenozoic faulting in the Kraishte area, SW Bulgaria. J Struct Geol 33:859—874. doi:10.1016/j.jsg.2011.03.006 Kounov A, Graf J, von Quadt A et al (2012) Evidence for a “Cado- mian” ophiolite ...
    ... 556"N). Length of hammer 330 mm Int J Earth Sci (Geol Rundsch) (2017) 106:1665–1692 Fig.6 Simplified tectonic map of the study area with arrows representing local directions of tectonic transport. See text for i w details N O 42 *% 0' N || ~ N y j }a ~ AOI NM / i w\ S 1673 “ ...

  • Age of the Jurassic hemipelagic sediments from the Ljubiš area (Zlatibor Mt., SW Serbia)

    Nikita Bragin, Nevenka Đerić (2020)
    Radiolaria, Dinarides, Jurassic, stratigraphy, Serbia
    ... ration of the esteemed Nataša GERZINA. REFERENCES AUBOUIN, J., BONNEAU, M., CELET, P., CHARVET, J., CLEMENT, B., DEGAR­ DIN, J.M., DERCOURT, J., FERRIÈRE, J., FLEURY, J.J., GUERNET, C., MAIL­ LOT, H., MANIA, J.H., MANSY, J.L., TERRY, J., THIEBAULT, P., TSOFLIAS, P. & VERRIEUZ, J.J. (1970): Contribution ...
    ... CONTI, M., CORTESE, G., DANELIAN, T., DE WEVER, P., DUMITRICA, P., DUMITRICA-JUD, R., GORIČAN, Š., GUEX, J., HULL, D., KITO, N., MARCUCCI, M., MATSUOKA, A., MURCHEY, B., O’DOGHERTY, L., SAVARY, J., VISHNEVSKAYA, V., WIDZ, D. & YAO, A. (1995b): Middle Jurassic to Early Cretaceous radiolarian biochronology ...
    ... Abhandlungen, 288/1, 1–47. GAWLICK, H.-J., SUDAR, M.N., MISSONI, S., SUZUKI, H., LEIN, R. & JOVANOVIĆ, D. (2017): Jurassic geodynamic history of the Dinaridic Ophiolote Belt (Innere Dinarides, SW Serbia).– Journal of Alpine Geology, 55, 1–167. GAWLICK, H.-J., SUDAR, M., SUZUKI, H., DJERIĆ, N., MISSONI ...

  • Integrated Stratigraphy of the Middle–Upper Jurassic of the Krížna Nappe, Tatra Mountains

    Renata Jach, Nevenka Đerić, Špela Goričan, Daniela Reháková (2014)
    carbon and oxygen isotopes, radiolarians, calcareous dinoflagellates, radiolarites, Krížna Nappe, West ern Carpathians, Tethys
    ... emo{el SYN PNEL SIM EeneL evsuetjog uBiH SHW B J J UJ93S9/A UPIUOUJIL 6 seuozv[) j O O seuoz| ·aGenoujp |6 900ZvT\ Š S_E_Mu„u_ _ -- e b n a n u o / g d v |pijjeuo!d|eO| s n o a u e o j e D | u e l e j o i p e x e v eyruuouuuv O L SZ O S 0 ...
    ... southern Spain). Facies, 55: 80-102. Nembčok, J., Bezak, Y., Biely, A., Gorek, A., Gross, P., Halouzka, R., Janak, M., Kahan, S., Kotanski, Z., Lefeld, J., Mello, J., Reichwalder, P., Raczkowski, W., Roniewicz, P., Ryka, W., Wieczorek, J. & Zelman, J., 1994. Geologickd mapa Tatier (Geological ...
    ... o18b[ogd 'g '(g66 1 *D{suAZozsnir)) }os y p o j S o d u t o ) *V 'O1ssbJnf oye'|-O|pp!}A| 2U} 10J e}ep odojosi!-uoq1eo Jo uO!JP|[9.102,) | 001 8LH sejduues 0 9|0uM B e p e u e o v pueRo0Os m s e j u u j j e q g c:m_mww MeN O PISSDOJ A ĐOUIAOJGj ...

  • A survey of greenhouse gases production in central European lignites

    Anna Pytlak, Anna Szafranek-Nakonieczna, Weronika Goraj, Izabela Śnieżyńska, Aleksandra Krążała, Artur Banach, Ivica Ristović, Mirosław Słowakiewicz, Zofia Stępniewska (2021)
    Lignit, Gasovi sa efektom staklene bašte, Ugljen dioksid, Metan, Azotni oksid
    ... ‘Adamów’ brown coal mines. J. Ecol. Eng. 16, 138–143. https:// doi.org/10.12911/22998993/60470. Gläßer, C., Groth, D., Frauendorf, J., 2011. Monitoring of hydrochemical parameters of lig- nite mining lakes in Central Germany using airborne hyperspectral casi-scanner data. Int. J. Coal Geol. 86, 40–53. ...
    ... nadkladu w Koninskim Zaglebiu Wegla Brunatnego, Przeglad Geologiczny. Myhre, G., Shindell, D., Bréon, F., Collins, W., Fuglestvedt, J., Huang, J., Koch, D., Lamarque, J., Lee, D., Mendoza, B., Nakajima, T., Robock, A., Stephens, G., Takemura, T., Zhan, H., 2013. Anthropogenic and natural radiative forcing ...
    ... measures. Geomicrobiol J. 31, 737–747. https://doi.org/10.1080/01490451.2014.889783. Pytlak, A., Sujak, A., Szafranek-Nakonieczna, A., Grzadziel, J., Banach, A., Goraj,W., Galazka, A., Gruszecki, W.I., Stepniewska, Z., 2020a. Water-induced molecular changes of hard coals and lignites. Int. J. Coal Geol. 224 ...

  • Određivanje sadržaja kiselih funkcionalnih grupa na površini biougljeva primenom Boehm-ovih titracija

    Aleksandar D. Krstić, Aleksandar Đ. Lolić, Marija A. Ilić, Aleksandar M. Mijatović, Snežana J. Zlatanović, Zoran P. Nedić, Vesna M. Pavelkić (2015)
    Biougalj se dobija pirolizom iz organskog otpada. Smatra se ,,modifikatorom'' zemljišta i koristi se kao đubrivo i kao rezervoar za skladištenje ugljenika. Kvantifikacija funkcionalih grupa je važna zbog hemijske reaktivnosti biougljeva koji imaju uticaj na svojstva zemljišta. U istraživanju su korišćena 3 uzorka biouglja različitog porekla i jedan referentni, aktivni ugalj. Sadržaj kiselih funkcionalnih grupa je određivan titracijom po Boehm-u na dva načina: uvođenje N2 tokom titracije i tretman sa BaCl2. Optimizovan je način pripreme tri Boehm ova rastvora ...
    ... grupa na površini biougljeva primenom Boehm-ovih titracija Aleksandar D. Krstić, Aleksandar Đ. Lolić, Marija A. Ilić, Aleksandar M. Mijatović, Snežana J. Zlatanović, Zoran P. Nedić, Vesna M. Pavelkić Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] Određivanje ...
    ... grupa na površini biougljeva primenom Boehm-ovih titracija | Aleksandar D. Krstić, Aleksandar Đ. Lolić, Marija A. Ilić, Aleksandar M. Mijatović, Snežana J. Zlatanović, Zoran P. Nedić, Vesna M. Pavelkić | 52. savetovanja Srpskog hemijskog društva | 2015 | | http://dr.rgf.bg.ac.rs/s/repo/item/0005644 Дигитални ...
    ... na povréini biougljeva primenom Boehm-ovih titracija Aleksandar D. Krstié, Aleksandar D. Lolié, Marija A. li, Aleksandar M. Mijatovi¢*, ‘Snezana J. Zlatanovi¢'*, Zoran P. Nedi¢***, Vesna M. Pavelki¢**** Hemijski fakultet, Univerzitet u Beogradu, Studentski trg 12-16, Beograd, Srbija; *Rudarsk ...

  • Osnovi hidrogeologije

    Petar Dokmanović (2021)
    hidrogeologija, atmosferska voda, površinske vode, podzemne vode, vodni bilans, poroznost stena
    ... York 8. Davis, N. S. & De Wiest, R. J. M. (1966): Hydrogeology, New York/ London/ Sydney. 9. Delleur J, (2007): Ellementary Groundwater flow and transport processes, In: The Handbook of Groundwater Engineering (sec. edition), 3.1-3.42, Editor: Delleur J , CRC Press Taylor and Francis group, Boca ...
    ... of Groundwater, In: The Handbook of Groundwater Engineering (sec. edition), Editor: Delleur J , CRC Press Taylor and Francis group, Boca Raton-London-New York 47. Lehr J., Scott H., Gallagher B. & Voytek J. (1988): Design and construction of water wells, Van Nostrand Reinhold, New York 48. Ljvovič ...
    ... poljoprivrednog zemljišta. 10 O s n o v i h i d r o g e o l o g i j e I DEO U V O D 11 O s n o v i h i d r o g e o l o g i j e 1.POJAM, PREDMET IZUČAVANJA I PRAKTIČNI ZNAČAJ HIDROGEOLOGIJE Hidrogeologija ...

  • Идејно решење заштите површинског копа ,,Дрмно" од вода у периоду од 2030. године до краја експлоатације

    Јован Киселчић (2024)
    Системи одводњавања на површинским коповима као и други технички системи морају успешно извршавати своју функцију и са свим својим елементима издржавати сва предвиђена напрезања,а при томе бити једноставни и економични.Функција система одводњавања је да спречи доток, пре свега, подземних вода у површински коп и да у одређеном времену испумпа задате количине воде.У овом раду приказани системи одводњавања на површинском копу ,,Дрмно" у периоу од 2023.године до краја експлоатације и то систем одводњавања подземних вода и систем одводњавања површинских вода.На ...
    одводњавање, површински коп, угаљ
    ... eJIČKTDOHNIDOBOJUPBHBOCT BOJIĆ H3 J[pMHCKeE H3JaHH JE OKO H H3HaJL MaKCHMAJIHO J\03BOJbeHe BpeJiHocTu oJ 1000 uS/cm; yKyrHH0 rBo»Klje (Fe) – oHo Iro KapakTepurre J[pMHckKy H3JlaH je noBehaH cajnp:xaj TBOxxXlja H MaHraHa y 3HauajHHM KOHICHTPpaHJaMa, OJL MaKCHMAJIHO J[O3BOJbeHHX KOHneHrTpanuja 3a ...
    ... Ma y J(eJOBHMa TepeHa OKO TIOBPIHHHCKOT KOra /J[pMH0o, TJie IIOCTOJH OBOJUĐbCHOCT y IIJIHOKBapTapHHM IIIJEByHKOBHMAa H TIČCKOBHMA, KaO H y JIeJIOBHMa TepeHa TJI IIOCTOJH IHpeKTHa XHpaylnmHukKa Be3a H3JlaHH y TIOBJIATH H HOJUHHH II yrJbeHOr cCJIOJa HMaMO Behu cajlpxkaj cyar(para, MOK ce y J(eJIOBHMa ...
    ... /lyHantia, ripekHHyT Je rpoTHnaj peuHax BojJta J[yHapneM. Kopuro /lyHaBia je cana IIpeceueHO H IIpeKO HOBOT CIIOJHOT KaHajma 4 mnoBe3aHo ca KaHajiIoM 4-1. Peka Miaiana ce bopmupa y 2KaryOunu o)j1i BoJla cHa)xKHOT KapcTHor Bpcja. OJ Ilerpopna na Jo cBor ymriha y J{yHaB, rpejnicraBJba paBHHuapcky peky Koja ...

  • The Fuzzy–AHP Synthesis Model for Energy Security Assessment of the Serbian Natural Gas Sector

    Aleksandar R. Madžarević, Dejan D. Ivezić, Miloš L. Tanasijević, Marija A. Živković (2020)
    Natural gas is used for the production of almost 20% of total energy today. The natural gas security of the Republic of Serbia is an urgent strategic, political and security issue. Serbia is one of the most vulnerable countries in Southeast Europe, because it only has one supply route. This study is a contribution to efforts to better understand the factors affecting energy security through the implementation of a new methodology based on the fuzzy–AHP synthesis model for measuring ...
    energetska bezbednost, prirodni gas, fazi AHP, AHP višekriterijumska analiza, fazi teorija
    ...           ј      Е            −         −        ј      Е      −             −        ј      Е      −             −        ј      Е          −             −        ј      Е          −             −        ј      Е          −             −        ј      Е          −             −        ј      Е     ...
    ... IEF = 40 m3/€ for the class j = 10 was found for the natural gas sector, as well as the minimum value of the economic feasibility Index IEF = 1 m3/€ for the class j = 1. The remaining values for class j are: j = 2 IEF = A2min + (A2max − A2min)/9 = 1+(40 − 1)/9 = 5.333 j = 3 IEF = A2j=2 + (A2max − A2 ...
    ... 1)/9 = 9.667 j = 4 IEF = A2j=3 + (A2max − A2 min)/9 = 9.667 + (40 − 1)/9 = 14.000 j = 5 IEF = A2j=4 + (A2max − A2 min)/9 = 14.000 + (40 − 1)/9 = 18.333 j = 6 IEF = A2j=5 + (A2max − A2 min)/9 = 18.333 + (40 − 1)/9 = 22.667 j = 7 IEF = A2j=6 + (A2max − A2min)/9 = 22.667 + (40 − 1)/9 = 27.000 j = 8 IEF = A2j=7 ...

  • Gate Road Support Deformation Forecasting Based on Multivariate Singular Spectrum Analysis and Fuzzy Time Series

    Luka Crnogorac, Rade Tokalić, Zoran Gligorić, Aleksandar Milutinović, Suzana Lutovac, Aleksandar Ganić (2021)
    Underground mining engineers and planners in our country are faced with extremely difficult working conditions and a continuous shortage of money. Production disruptions are frequent and can sometimes last more than a week. During this time, gate road support is additionally exposed to rock stress and the result is its progressive deformation and the loss of functionality of gate roads. In such an environment, it is necessary to develop a low-cost methodology to maintain a gate road support system. ...
    deformacije podgrade, lasersko skeniranje, višekanalna singularna spektralna analiza, prognoza, klasterisanje fuzzy vremenskih serija
    ... on stage were also used for the forecasting purpose. Vector U(i)∇ j , j = 1, 2, composed of the first Li−1 components of the vector U(i) j , j = 1, 2, 3, 4, is represented in Table 11. Table 11. Components of the vector U(i) j , j = 1, 2. Marker UV 1 UV 2 1 0.0011 −0.0570 0.0020 −0.0639 2 0.0016 ...
    ... . . . . . . . . . . . . 19 0.2072 −0.0705 0.2065 −0.0628 Vector π(i)j , j = 3, composed of the last component of the vector U(i) j , (i = 1, . . . , M), is represented in Table 12. Table 12. Components of the vector π(i)j , j = 3. Marker UV 1 UV 2 1 0.0029 −0.0640 2 0.0037 −0.0744 . . . . . . ...
    ... matrix Ỹ(i) obtained from the previous step, whereH is a Hankel operator; assume U(i)∇ j denotes the vector of the first Li−1 components of the vector U(i) j and π (i) j is the last component of the vector U(i) j (i = 1, . . . , M); select the number of r eigentriples for the reconstruction stage that ...

  • Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach

    Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)
    Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...
    pyrazoloquinolinones, nanocrystals, wet media milling, fasted/fed bioavailability
    ... for the treatment of psychiatric illnesses. J. Control Release 2016, 223, 137–156. [CrossRef] [PubMed] 8. Peltonen, L.; Hirvonen, J. Pharmaceutical nanocrystals by nanomilling: Critical process parameters, particle fracturing and stabilization methods. J. Pharm. Pharmacol. 2010, 62, 1569–1579. [CrossRef] ...
    ... L.; Tyner, K.M. Development considerations for nanocrystal drug products. AAPS J. 2017, 19, 642–651. [CrossRef] [PubMed] 10. Gao, L.; Liu, G.; Ma, J.; Wang, X.; Zhou, L.; Li, X. Drug nanocrystals: In vivo performances. J. Control Release 2012, 160, 418–430. [CrossRef] [PubMed] 11. O’Shea, J.P.; Holm ...
    ... [CrossRef] 17. Wu, L.; Zhang, J.; Watanabe, W. Physical and chemical stability of drug nanoparticles. Adv. Drug Deliv. Rev. 2011, 63, 456–469. [CrossRef] 18. Li, J.; Wang, Z.; Zhang, H.; Gao, J.; Zheng, A. Progress in the development of stabilization strategies for nanocrystal preparations. Drug Deliv ...

  • A Model for Determining Fuzzy Evaluations of Partial Indicators of Availability for High-Capacity Continuous Systems at Coal Open Pits Using a Neuro-Fuzzy Inference System

    Miljan Gomilanović, Miloš Tanasijević, Saša Stepanović, Filip Miletić (2023)
    This paper presents a model for determining fuzzy evaluations of partial indicators of the availability of continuous systems at coal open pits using a neuro-fuzzy inference system. The system itself is a combination of fuzzy logic and artificial neural networks. The system availability is divided into partial indicators. By combining the fuzzy logic and artificial neural networks, a model is obtained that has the ability to learn and uses expert judgment for that learning. This paper deals with the ...
    системи, континуални системи експлоатације (роторни багер-транспортер-дробилично постројење), рударство, расположивост, меко рачунарство, фази логика, ANN, ANFIS

  • Numerical Models of Debris Flows with Entrainment Analysis-Case Studies from the Republic of Serbia

    Jelka Krušić , Biljana Abolmasov, Miloš Marjanović (2021)
    The results of material entrainment analysis in RAMMS debris flow software, as well as numerical models of final flow heights for two case studies from the Republic of Serbia are presented. Both of debris flow cases started with initial sliding of huge volume block, prolonging to behave as flowing process. Results of the analysis showed that entrainment material affects final results of transportation model, runout distance, deposition area and volume of debris flow. In both cases entrainment volume is very ...
    tecišta, zadržavanje nanosa, RAMMS, validacija