Претрага
471 items
-
Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study
Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...... the small particle size of nanocrystals makes them sus- ceptible to aggregation during storage, which is considered the major drawback of these systems (Wu et al., 2011; Li et al., 2021). For parenteral formulations, it is important to keep the particle size below 1 Hm; therefore, to extend shelf ...
... be performed at tempera- tures just below their eutectic point (-1.5 "C), so the combination of sucrose and mannitol has the advantages of both systems. With a suffi- cient amount of mannitol (at least 30%), the cake structure is secured by its crystallinity even if primary drying is carried out ...
... of mannitol and vice versa, and the nature of this interaction is mainly determined by their ratio. In a study by Jena et al. (2016) on frozen systems, mannitol crystallized in samples with a high mannitol-trehalose ratio, while trehalose remained in the amorphous state. This was considered an ...Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study" in European Journal of Pharmaceutical Sciences, Elsevier BV (2023). https://doi.org/10.1016/j.ejps.2023.106557
-
Regionalno-geološke karakteristike miocenskih sedimenata na prostoru severnog Banata
Dejan N. Radivojević (2014-12-30)Predmet doktorske disertacije predstavljalo je rešavanje strukturno‐stratigrafskihodnosa miocenskih sedimenata na prostoru severnog Banata. U cilju regionalnogsagledavanja, korišćeni su svi raspoloživi geofizički i geološki podaci sa širegistražnog područja, odnosno iz celog Panonskog basena i susednog orogena. Osimklasičnih metoda primenjene su i savremene metode seizmostratigrafije,tektonostratigrafije i riftne sekvencione stratigrafije. Primenjene metode omogućilesu izradu modela progradacije ivice šelfa za ceo Panonski basen, modela uzajamnihveza između basena i geodinamičkog modela jugoistočnog oboda basena.Jezero Panon je većim delom zapunjeno prilivom sedimenata paleo‐Dunavom saseverozapada, odnosno ...Centralni Paratetis, Panonski basen, miocen, jezero Panon,seizmostratigrafija, sekvenciona stratigrafija, paleogeografija, geodinamika... important systems progradation also appear from local river systems toward east and west across eastern margin and toward south and north across southern margin of Pannonian Basin. The final stage of Lake Pannon fill appear in place where two deltaic systems reach each ...
... Province, Central Europe (Province 4808) – Petroleum geology, total petroleum systems, and petroleum resource assessment, U.S. Geological Survey Bulletin 2204–B, 47 pp. Doust, H., 2003, Placing petroleum systems and plays in their basin history context: a means to assist in the identification ...
... ulazi u Rumuniju. U cilju određivanja vremensko‐prostornih odnosa miocenske ekstenzije primenjen je koncept tektonskih sistemskih pojaseva (tectonic systems tract), što je pomoglo i u određivanju mehanizma i vremena formiranja basena. Evolucioni model Panonskog basena podrazumevao je početak ekstenzije ...Dejan N. Radivojević. "Regionalno-geološke karakteristike miocenskih sedimenata na prostoru severnog Banata" in Универзитет у Београду, Универзитет у Београду, Рударско-геолошки факултет (2014-12-30)
-
A bilingual digital library for academic and entrepreneurial knowledge management
A generic knowledge management process of organization, storage and retrieval of knowledge can suitably be fitted in a digital library. In the digital and knowledge age digital libraries can be used in knowledge management to handle intellectual assets and support knowledge creation. A multilingual digital library either stores content in more than one language or provides multilingual query access to monolingual content. In Serbia 18 of 308 scientific journals regularly published are bi-lingual, with papers simultaneously being in English ...... searching, linguistic analysis, semantic networks, knowledge extraction, etc. should be a part of recent developments in knowledge management systems. DL researchers have a need to transform information access into knowledge creation. Instead of serving as information providers, DL could become ...
... our days while digital libraries provide extraordinary information and knowledge highways for all. Lytras outlines the need for building library systems that go a step beyond the existing technological infrastructure and present an attempt to clarify the main directions for research on the concept ...Ranka Stanković, Cvetana Krstev, Biljana Lazić, Dalibor Vorkapić. "A bilingual digital library for academic and entrepreneurial knowledge management" in Proceeding of 10th International Forum on Knowledge Asset Dynamics — IFKAD 2015: Culture, Innovation and Entrepreneurship: connecting the knowledge dots, Bari, Italy, 10-12 June 2015, Bari : IFKAD (2015)
-
Terminology Acquisition and Description Using Lexical Resources and Local Grammars
Acquisition of new terminology from specific domains and its adequate description within terminological dictionaries is a complex task, especially for languages that are morphologically complex such as Serbian. In this paper we present an approach to solving this task semi-automatically on basis of lexical resources and local grammars developed for Serbian. Special attention is given to automatic inflectional class prediction for simple adjectives and nouns and the use of syntactic graphs for extraction of Multi-Word Unit (MWU) candidates for ...... Relation between word endings and inflectional FST classes The process of automatic prediction of inflec- tional FST class for a new entry follows a hybrid approach: one part is rule-driven with explicit codification of knowledge about FST classes and the other is statistical, based on existing diction- ...
... Adaptable Terminology Acquisi- tion. In Z. Kedad, N. Lammari, E. Métais, F. Meziane & Y. Rezgui (Eds.), Natural Language Processing and Information Systems (Vol. 4592: 420-426): Springer Berlin Heidelberg. Courtois, B., Silberztein, M. (1990). Dictionnaires électroniques du français. Larousse, Paris ...
... Compari- son with General Reference Corpus. In C. Hopfe, Y. Rezgui, E. Métais, A. Preece & H. Li (Eds.), Natural Language Processing and Information Systems (Vol. 6177, pp. 248-255): Springer Berlin Heidelberg. Justeson, J. S., & Katz, S. M. (1995). Technical ter- minology: some linguistic properties and ...Cvetana Krstev, Ranka Stanković, Ivan Obradović, Biljana Lazić. "Terminology Acquisition and Description Using Lexical Resources and Local Grammars" in Proceedings of the 11th Conference on Terminology and Artificial Intelligence, Granada, Spain, 2015, Granada : LexiCon (Universidad de Granada) (2015)
-
Wordnet Development Using a Multifunctional Tool
Ivan Obradović, Ranka Stanković (2007)In this paper we present a multifunctional tool for manipulating heterogeneous language resources. The tool handles electronic dictionaries, wordnets and aligned texts, and provides for their synchronous use in various tasks. We focus here on the description of the possibilities this tool offers in the development of wordnets. Besides the wordnet module which enables parallel handling of two wordnets, other modules, such as the module for morphological dictionaries and the module for aligned texts, as well as available finite ...... Unitex, based on LADL format and supporting resources in Unicode has been developed in parallel, and is also available 6 . Since all three systems (Intex, Unitex, and NooJ) provide for processing of texts on basis of dictionaries, in combination with regular expressions and FSTs, and each ...
... activate the functions of the Intex, Unitex and/or NooJ system, and select a list of dictionaries he/she wants to use. As none of the three systems offers possibilities for managing the content of dictionaries themselves, the WS4LR dictionary management module has been developed to enable the ...Ivan Obradović, Ranka Stanković. "Wordnet Development Using a Multifunctional Tool" in Proceedings of the International Workshop Computer Aided Language Processing (CALP) '2007, Borovets, Bulgaria, September 2007, - (2007)
-
Ostvarivanje dobiti pri uvođenju sistema agregatnih zamena na osnovnoj rudarskoj mehanizaciji površinskih kopova EPS
Jedan od osnovnih zadataka na površinskim kopovima uglja je ostvarivanje zadovoljavajućeg vremenskog i kapacitetnog iskorišćenja kontinualnih sistema. Da bi se to postiglo, neophodno je izvršiti izmene u postojećoj strategiji održavanja. Preduslov je uvođenje agregatne zamene vitalnih delova na rudarskim mašinama. Benefiti su višestruki. Očekivani rezultati ovakvog pristupa su: smanjenje zastoja i povećanje vremena rada; direktne materijalne uštede; bolja organizacija rada; racionalizaciju radioničkih i magacinskih kapaciteta; povećanje vrednosti mašina. Da bi se uvela agregatna zamena neophodne su investicije za nabavku ...Predrag Jovančić, Ignjatović Dragan, Đenadić Stevan. "Ostvarivanje dobiti pri uvođenju sistema agregatnih zamena na osnovnoj rudarskoj mehanizaciji površinskih kopova EPS" in X Međunarodna konferencija UGALJ, Zlatibor, Srbija, 13-16. Oktobar 2021., Jugoslovenski komitet za površinsku eksploataciju (2021)
-
Understanding the effect of synthesis and sintering temperature on the functional properties of barium titanate/cobalt ferrite composites
Marija Šuljagić, Aleksandar Kremenović, Ivan Petronijević, Adis Džunuzović, Miljana Mirković, Vladimir Pavlović, Ljubica Anđelković (2023)To investigate the effect of synthesis procedure and sintering temperature on the functional properties of perovskite/spinel ceramics, BaTiO3/CoFe2O4 composites were prepared by thermal decomposition, coprecipitation, and microemulsion method, and sintered at 1150°C and 1300°C. The phase composition and morphology of as-prepared powders as well as sintered ceramics were thoroughly examined by X-ray powder diffraction (XRPD) and scanning electron microscopy (SEM) coupled with electron dispersive spectroscopy (EDS). The dielectric and ferroelectric measurements were performed in detail. Generally, the ...Marija Šuljagić, Aleksandar Kremenović, Ivan Petronijević, Adis Džunuzović, Miljana Mirković, Vladimir Pavlović, Ljubica Anđelković. "Understanding the effect of synthesis and sintering temperature on the functional properties of barium titanate/cobalt ferrite composites" in Science of Sintering (2023). https://doi.org/10.2298/SOS220512013S
-
Smanjenje sleganja plitkih temelja primenom mikrošipova
Slobodan Ćorić, Dragoslav Rakić (2021)Mikrošipovi su šipovi malog prečnika koji se grade tako što se u tlu specijalni postupkom formira bušotina koja se zatim armira i injektira. Njihov prečnik je najčešće 150 – 300 mm, a dužina može da bude i više desetina metara. Mikrošipovi mogu da se grade u svim vrstama tla i mogu da budu vertikalni i kosi. Oni se, stoga, koriste kao zamena za konvencionalne šipove i ankere. Primena mikrošipova u fundiranju predstavlja jedan savremeni način izgradnje i sanacije temelja/objekata. ...Slobodan Ćorić, Dragoslav Rakić. "Smanjenje sleganja plitkih temelja primenom mikrošipova" in Zbornik radova međunarodno naučno-stručnog savetovanja Zemljotresno inženjerstvo i geotehnički aspekti građevinarstva, Vrnjačka banja, 3-5. novembar 2021., Beograd : Savez građevinskih inženjera Srbije (2021)
-
A survey of greenhouse gases production in central European lignites
Anna Pytlak, Anna Szafranek-Nakonieczna, Weronika Goraj, Izabela Śnieżyńska, Aleksandra Krążała, Artur Banach, Ivica Ristović, Mirosław Słowakiewicz, Zofia Stępniewska (2021)... and the role of the State Geological Institute. Geol. Q. 35, 207–220. Cole, J.J., Prairie, Y.T., 2014. Dissolved CO2 in freshwater systems? Reference Module in Earth Systems and Environmental Sciences. Elsevier https://doi.org/10.1016/b978- 0-12-409548-9.09399-4 DeAngelis, K.M., Allgaier, M., Chavarria ...
... solu- bility of CO2 decreases substantially, thus, water chemistry has a huge impact on the buffering of lignite-originating CO2 emissions. Lake eco- systems are also a habitat of methanotrophic bacteria, whichmay effec- tively reduce methane emissions. However, the majority of mesophilic methanotrophic ...Anna Pytlak, Anna Szafranek-Nakonieczna, Weronika Goraj, Izabela Śnieżyńska, Aleksandra Krążała, Artur Banach, Ivica Ristović, Mirosław Słowakiewicz, Zofia Stępniewska. "A survey of greenhouse gases production in central European lignites" in Science of The Total Environment, Elsevier (2021). https://doi.org/10.1016/j.scitotenv.2021.149551
-
The subthermal potential of karstic groundwater of Kučaj–Beljanica region in Serbia estimated by the multivariate analysis
Earth-Surface Processes, Geology, Pollution, Soil Science, Water Science and Technology, Environmental Chemistry, Global and Planetary ChangeLjiljana Vasić, Dragana Ž. Živojinovic, Vladana Rajaković-Ognjanović, Huang Fen, Cao Jianhua. "The subthermal potential of karstic groundwater of Kučaj–Beljanica region in Serbia estimated by the multivariate analysis" in Environmental Earth Sciences, Springer Science and Business Media LLC (2021). https://doi.org/10.1007/s12665-021-09392-1
-
Supstitucione reakcije Pd(II) kompleksa sa biološki važnim biomolekulima
Aleksandar M. Mijatović, Jovana Bogojeski. "Supstitucione reakcije Pd(II) kompleksa sa biološki važnim biomolekulima" in Hemijski pregled, Srpsko hemijsko društvo (2017)
-
The interaction of organoselenium trans-palladium(II) complexes toward small-biomolecules and CT-DNA
Serija organoselenijum trans-paladijum(II) kompleksa 1 (bis(2-(fenilselanilmetil)oksolan)dihloropaladijum(II)), 2 (bis(2-(fenilselanilmetil)oksan)dihloropaladijum(II)) i 3 (bis(2) ,2-dimetil-3-(fenilselanil)oksan)dihloropaladijum(II)) su korišćeni za ispitivanje reaktivnosti ovog specifičnog tipa kompleksa prema različitim bio-molekulima. Ovaj sistem je od posebnog interesa jer se jako malo zna o supstitucionim reakcijam organoselenijum paladijum(II) kompleksa sa trans konfiguracijom. Zamena koordinovanog hlorida sa serijom malih bio-molekula (l-Met, l-His, l-Cis, GSH i 5′-GMP) proučavana je pod uslovima pseudo-prvog reda kao funkcija koncentracije nukleofila i temperature korišćenjem tehnika zaustavljenog toka. Rezultati za proučavane komplekse ukazuju da ...Vera M. Divac, Aleksandar Mijatović, Marina D. Kostić, Jovana Bogojeski. "The interaction of organoselenium trans-palladium(II) complexes toward small-biomolecules and CT-DNA" in Inorganica Chimica Acta, Elsevier BV (2017). https://doi.org/10.1016/j.ica.2017.07.012
-
Vebran Web Services for Corpus Query Expansion
Ranka Stanković, Miloš Utvić (2020)U ovom radu se govori o razvoju veb usluga Vebran i njihovoj primeni u poboljšanju pretraživanja korpusa. Veb-servisi Vebran koriste se za konsultovanje spoljnih leksičkih izvora za srpski jezik (uglavnom elektronski morfološki rečnici i srpski Vordnet) i proširivanje korisničkih upita radi dobijanja relevantnijih rezultata iz srpskih korpusa.... external lexical resources and produce regular expressions that improve re- call of the retrieved inflected forms for a given lemma. The described hybrid approach was successfully tested by modifying the web interface of corpus search tools OCWB and NoSketch Engine. Vebran web services are currently ...
... lexical masks, new semantic markers relevant to the field of mining have been integrated (Обрадовић et al., 2017). 2.3 Corpora tools Three different systems for diverse types of usage scenarios are used in this research: – Unitex (Paumier, 2016; Krstev, 2008); – Open Corpus Workbench (OCWB) (Evert and ...
... corpus processor with user-friendly interface, language resources distributed out-of- the-box and set of functions that can be used from other software systems. The Unitex NLP engine is based on automata-oriented technology, allowing users to 1) Compile rules and dictionaries as finite-state machines; 2) Use ...Ranka Stanković, Miloš Utvić. "Vebran Web Services for Corpus Query Expansion" in Infotheca, Faculty of Philology, University of Belgrade (2020). https://doi.org/10.18485/infotheca.2019.19.2.5
-
Природни потенцијал минералних вода Србије - Natural potential of mineral waters in Serbia
Оливера Крунић (2021)Оливера Крунић. "Природни потенцијал минералних вода Србије - Natural potential of mineral waters in Serbia" in Рационално коришћење земљишта и вода у Србији - Sustainable Use of Land and Water in Serbia- Serbian Academy of Sciences and Arts; Scientific Conferences Volume CXCVII; Department of Chemical and Biological Sciences, Book 19, Српска академија наука и уметности (2021)
-
Optimisation of underground mine decline development system using genetic algorithm
... Gligorić Z.; Ganić A.; Tokalić R.; Milutinović A. REFERENCES 1 ALI, F.A. (2014) A novel hybrid genetic differential evolution algorithm for constrained optimization problems. International Journal of Advanced Computer Science and Applications ...
... When deposit is composed of few ore bodies it is necessary to interconnect them into one integrated system. There are different development systems (shaft, decline, adit) which can be used to create such system. Suppose the deposit characteristics indicate that decline development system is ...Zoran Gligorić, Aleksandar Ganić, Rade Tokalić, Aleksandar Milutinović. "Optimisation of underground mine decline development system using genetic algorithm" in Underground mining engineering, Beograd : Univerzitet u Beogradu – Rudarsko–geološki fakultet (2014)
-
Energetska efikasnost elektromotora na površinskim kopovima
Snežana Aleksandrović, Ilija Jeftenić (2023)Snežana Aleksandrović, Ilija Jeftenić. "Energetska efikasnost elektromotora na površinskim kopovima" in 11. Međunarodna konferencija “Ugalj i kritični materijali" CCM 2023, Zlatibor, 11-14. oktobar 2023. , Beograd : Jugoslovenski komitet za površinsku eksploataciju (2023)
-
Ontološki model upravljanja rizikom u rudarstvu
Olivera Kitanović (2021)Rudarska proizvodnja obuhvata kompleksne tehnološke sisteme, što nameće potrebu za uspostavljanjem i unapređivanjem sistema upravljanja rizikom. Heterogenost i obim podataka neophodnih za upravljanje rizikom zahtevaju sistem koji ih na fleksibilan način integriše i omogućava njihovo optimalno korišćenje. Osnovni cilj ove disertacije je razvoj ontologije za domen rudarstva i na njoj zasnovanog modela za upravljanje rizikom. Njegova realizacija podrazumeva i implementaciju algoritama ekstrakcije informacija za popunjavanje ontologije, kao i odgovarajuće softversko rešenje. Razvoj modela obuhvata i značajno proširenje rudarskog korpusa, kao ...rudarstvo, rizik, upravljanje rizikom, procena rizika, ontologija, semantička mreža, ekstrakcija informacija, upravljanje znanjem, računarska lingvistika... Radosavljević. 2009. “Risk Assessment and Managing Technical Systems in Case of Mining Industry.” Strojniški Vestnik-Journal of Mechanical Engineering 55 (2): 119–13. Lilić, Nikola, Ivan Obradović, and Aleksandar Cvjetić. 2010. “An Intelligent Hybrid System for Surface Coal Mine Safety Analysis.” Engineering ...
... ONTOLOGY-BASED MODEL FOR RISK MANAGEMENT IN MINING Abstract Mining production involves complex technological systems, which calls for the need to create and improve risk management systems. The heterogeneity and scope of data necessary for risk management require a system that integrates them in a ...
... International Journal of Intelligent Engineering and Systems 12 (2): 170–81. Alanen, Jarmo, Iiro Vidberg, Heikki Nikula, Nikolaos Papakonstantinou, Teppo Pirttioja, and Seppo Sierla. 2011. “Engineering Data Model for Machine Automation Systems.” Allan, G. M., N. D. Allan, V. Kadirkamanathan, and P ...Olivera Kitanović. Ontološki model upravljanja rizikom u rudarstvu, Beograd : [O. Kitanović], 2021
-
A multi-criteria approach for assessing the potential of renewable energy sources for electricity generation: Case Serbia
When assessing the potential of renewable energy alternatives for electricity generation, it is necessary to implement a multi-perspective approach that includes economic, technical, environmental, and socio-political criteria. For the evaluation of criteria and alternatives, the Fuzzy Analytical Hierarchy Process (FAHP) method is applied. The obtained weights are formed according to the values of energy indicators and expert judgments. The use of a fuzzy numerical value scale for the assessment of expert judgments and energy indicators provides a more sensitive ...... 120352. Rathi, R., Prakash, C., Singh, S., Krolczyk, G., Pruncu, C.I., 2020. Measurement and analysis of wind energy potential using fuzzy based hybrid MADM approach. Energy Rep 6 (2020), 228–237. Ren, J., Sovacool, B.K., 2014. Enhancing China’s energy security: Determining influential factors and ...
... fossil fuels to one that increases the efficiency and share of renewables (IRE, 2018). A transition to- wards long-term sustainability in global energy systems based on renewable energy sources (RESs) can simultaneously miti- gate issues such as greenhouse gas emissions, pollution, and the exceeding of critical ...
... renewable energy sources have become a powerful and cost- effective source for electricity generation. The costs of the imple- mentation of RESs in energy systems are substantially reduced so in some regions of the U.S and Europe, electricity from RESs could become cheaper than electricity produced from traditional ...Boban Pavlović, Dejan Ivezić, Marija Živković. "A multi-criteria approach for assessing the potential of renewable energy sources for electricity generation: Case Serbia" in Energy Reports, Elsevier BV (2021). https://doi.org/10.1016/j.egyr.2021.02.072
-
Hydrochemical features and their controlling factors in the Kucaj-Beljanica Massif, Serbia
Earth-Surface Processes, Geology, Pollution, Soil Science, Water Science and Technology, Environmental Chemistry, Global and Planetary ChangeFen Huang, Ljiljana Vasic, Xia Wu, Jianhua Cao, Saša Milanovic. "Hydrochemical features and their controlling factors in the Kucaj-Beljanica Massif, Serbia" in Environmental Earth Sciences, Springer Science and Business Media LLC (2019). https://doi.org/10.1007/s12665-019-8452-4
-
An Integrated Environment for Management and Exploitation of Linguistic Resources
Ranka Stanković, Ivan Obradović (2009)... became more and more frequently used. Thus two new systems, Unitex [8] and Nooj [9] were developed, both allowing the processing of texts in Unicode, and subse- quently started to suppress Intex. Although text processing in all three systems is based on dictionaries in LADL for- mat, none of ...Ranka Stanković, Ivan Obradović. "An Integrated Environment for Management and Exploitation of Linguistic Resources" in Proceedings of the International Multiconference on Computer Science and Information Technology, Computational Linguistics – Applications Workshop (CLA09), Mrągowo, Poland, October 2009, Piscataway : IEEE (2009)