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1597 items
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Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study
Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...... (XRPD). The analysis was performed on a Rigaku Smartlab X-ray diffractometer in a 0-0 geometry using the D/teX Ultra 250 strip detector in 1D standard mode with a CuKou „ radiation source (U=40 kV and I=30 mA). Data were acquired in a 20 range of 3-40% using a low background single crystal silicon ...
... of the lyophilzates was analyzed by scanning elec- tron microscopy (SEM). A small amount of the sample was placed on a conductive double-sided adhesive tape and examined with a Zeiss Ultra Plus 55 or Zeiss DSM 940 A microscope (Carl Zeiss GmbH, Oberkochen, Germany). Photomicrographs were taken ...
... Yurquina, A., Locatelli, S., Brandšn, S.A., 2012. A complete characterization of the vibrational spectra of sucrose. Carbohydr. Res. 361, 212–218. https://doi.org/10.1016/j.carres.2012.07.009. Bruni, G., Berbenni, V., Milanese, C., Girella, A., Cofrancesco, P., Bellazzi, G., Marini, A., 2009. P ...Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study" in European Journal of Pharmaceutical Sciences, Elsevier BV (2023). https://doi.org/10.1016/j.ejps.2023.106557
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GNSS Time Series as a Tool for Seismic Activity Analysis Related to Infrastructure Utilities
... structures. Simplified tectonic map of the Albania region presented in Fig. 1. Albania is a Balkan country with a high rate of seismicity. The west coast of Albania is a convergent plate boundary and there is a fold and thrust belt. Adria plate is diving beneath the Eurasia plate to form the Adriatic ...
... metadata, and data flow. Used GNSS stations are Class A stations (positions with 1 cm accuracy at all epochs of the period of the used observations). Coseismic deformation is investigated using these stations. By looking at data from a GNSS stations over a period of time, we can determine whether the ground ...
... from a GNSS network, it is possible to get a larger view of which areas of the surface are moving as well as the speed and direction of movement. 250 S. Tucikešić et al. 2.2 Seismic Data Albania lies across the convergent boundary between the Eurasian Plate and the Adriatic Plate, as a part of ...Sanja Tucikešić, Ankica Milinković, Branko Božić, Ivana Vasiljević, Mladen Slijepčević . "GNSS Time Series as a Tool for Seismic Activity Analysis Related to Infrastructure Utilities" in Contributions to International Conferences on Engineering Surveying. Springer Proceedings in Earth and Environmental Sciences, Dubrovnik, Croatia, October 22-23, 2020, Springer, Cham (2021). https://doi.org/10.1007/978-3-030-51953-7_21
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WebGIS Cadastre of Abandoned Mines in Autonomous Province of Vojvodina
Ranka Stanković, Nikola Vulović, Nikola Lilić, Ivan Obradović, Radule Tošović, Milica Pešić-Georgiadis (2015)Ranka Stanković, Nikola Vulović, Nikola Lilić, Ivan Obradović, Radule Tošović, Milica Pešić-Georgiadis. "WebGIS Cadastre of Abandoned Mines in Autonomous Province of Vojvodina" in Proceedings of the 5th International Symposium Mining And Environmental Protection,June 10-13,2015, Vrdnik, Serbia, Belgrade : Faculty of Mining and Geology (2015)
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Early–Middle Jurassic brachiopods from Ponor Mountain, Western Balkan Mountains, Bulgaria; taxonomy, biostratigraphy and occurrence in the context of the early Toarcian Oceanic Anoxic Event
Barbara V. Radulović, Lubomir S. Metodiev, Neda Motchurova-Dekova, Platon Tchoumatchenco. "Early–Middle Jurassic brachiopods from Ponor Mountain, Western Balkan Mountains, Bulgaria; taxonomy, biostratigraphy and occurrence in the context of the early Toarcian Oceanic Anoxic Event" in Historical Biology (2023). https://doi.org/10.1080/08912963.2023.2190757
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Determining threaded machine element fabrication technology by pulsed thermography
Stevan Jovičić, Ljubiša Tomić, Aleksandar Kovačević, Nenad Munić, Vesna Damnjanović. "Determining threaded machine element fabrication technology by pulsed thermography" in Science of Sintering, National Library of Serbia (2024). https://doi.org/10.2298/sos240112005j
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Tectonic evolution of the Circum-Moesian orocline of the Carpatho-Balkanides: Paleomagnetic constraints
Emő Márton, Vesna Cvetkov, Miodrag Banješević, Gábor Imre, Aleksandar Pačevski. "Tectonic evolution of the Circum-Moesian orocline of the Carpatho-Balkanides: Paleomagnetic constraints" in Journal of Geodynamics, Elsevier BV (2024). https://doi.org/10.1016/j.jog.2024.102058
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Effects of Energy Production and Consumption on Air Pollution in Serbia
Marija Živković (2019)Energy production and combustion, mostly from unregulated or inefficient fuel combustion, are the single most important anthropogenic sources of air pollutant emissions. Energy sector in Serbia is highly fossil fuel intensive: 87.88% of energy consumed in Serbia is related to fossil fuels, while almost 95% of energy sources are combusted. In 2017. energy related carbon dioxide emission in Serbia is was 47.95 million tones. The main source of carbon dioxide emission was coal, responsible for almost 70% of energy ...Marija Živković. "Effects of Energy Production and Consumption on Air Pollution in Serbia" in Mining and Environmental Protection-MEP 2019, University of Belgrade, Faculty of Mining and Geology (2019)
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Groundwater gravitational circulation of Karst Veliko Vrelo and Malo Vrelo springs by isotope and the noble gas method: case study of the Beljanica Massif
Earth-Surface Processes, Geology, Pollution, Soil Science, Water Science and Technology, Environmental ChemistryLjiljana Vasić, Laszlo Palcsu, Huang Fen. "Groundwater gravitational circulation of Karst Veliko Vrelo and Malo Vrelo springs by isotope and the noble gas method: case study of the Beljanica Massif" in Environmental Earth Sciences, Springer Science and Business Media LLC (2019). https://doi.org/10.1007/s12665-019-8294-0
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Ventex: an expert system for mine ventilation systems analysis
roblems relating to mine ventilation systems analysis are usually of a very complex nature. They involve the estimation of numerous interdependent parameters pertaining to the network status, ventilation status, ventilation system stability, air current losses, climate conditions, gas state, fire risk and dangerous dust pollution risk. The solution to these problems relies, to a great extent, on numerical methods. With the development of computer technology these methods were incorporated as numerical routes in software packages, such as the mine ...... declarative knowledge are needed for a successful solution of problems in mine ventilation systems analysis. This paper describes an approach to mine ventilation systems analysis which is based on a symbolic upgrading of the numerical Sim Vent system. The result is VENTEX, a coupled expert system incorporating ...
... encapsulated by numerical routines, the complexity of the subject matter requires a high level of expert knowledge and experience. This knowledge pertains to the heuristics experts use when they apply numerical methods and it takes a symbolic form, very often that of rules, being thus declarative in its character ...
... e knowledge, that offers the possibility for a more profound exploitation of the available software at an expert level. The paper presents the global strategy of mine ventilation system analysis used in the VENTEX system and its formalisation using a modi�cation of the object-oriented analysis model ...Nikola Lilić, Ranka Stanković, Ivan Obradović. "Ventex: an expert system for mine ventilation systems analysis" in Mining Technology, United Kingdom (1997)
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From Mid-Jurassic extension to obduction-related Mélange Formation: Sedimentary records from a displaced segment of the Adriatic passive margin (NE Hungary)
Szilvia Kövér, János Haas, Nevenka Đerić, Ottilia Szives, Péter Ozsvárt, László Fodor. "From Mid-Jurassic extension to obduction-related Mélange Formation: Sedimentary records from a displaced segment of the Adriatic passive margin (NE Hungary)" in 18th Workshop of the International Lithosphere Program Task Force Sedimentary Basins, Kraków, Poland, 07–11. October 2024, Polish Geological Society (2024)
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Debris-flow Susceptibility Assessment in Flow-R: Ribnica River Case Study
Debris flows are among the most dangerous erosional geohazards due to the fast rate of movement and long runout zones. Even though the initiation can be triggered in mountainous areas, inhabited and with steep slopes, their propagation and deposition can endanger not only buildings and infrastructure in the urbanized areas, but also threaten human lives. As these initiation areas usually represent unattainable terrains with rapid vegetation cover development, field observations and aerial photo analysis become high-demanding tasks. Consequently, medium-to-regional ...Ksenija Micić, Miloš Marjanović, Biljana Abolmasov . "Debris-flow Susceptibility Assessment in Flow-R: Ribnica River Case Study" in Proceeding of the 6th Regional Symposium on Landslides in the Adriatic-Balkan Region, ReSyLAB 2024, University of Belgrade, Faculty of Mining and Geology (2024). https://doi.org/https://doi.org/10.18485/resylab.2024.6
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Upper Miocene depositional environments of the Kikinda-Mokrin High (Serbia)
Saša Ivanišević, Dejan Radivojević (2018)Exploration for oil and gas in mature areas, such as the Pannonian Basin, can benefit from reexamination of old data using more advanced modern workflows that focus on the temporal and spatial aspects of sediment deposition. Specifically, we apply a new environment of deposition model that interprets the Upper Miocene- Pliocene sediments as being deposited in a rapidly filling basin characterized by quick shelf edge progradation from the northwest toward the southeast. Reconstruction of this shelf edge trajectory reveals ...... (Sztanó et al., 2013), it could be concluded that the postrift sediments were deposited as a transgressive sys- tems tract (TST) and a highstand systems tract (HST). Huge influx of sediments dur- ing this period formed a thick sequence in which basinal plain, slope, and delta sedi- ments could be distinguished ...
... suggest that the Szeged fault was a partial barrier to hydrocarbon migration. In addition to the marls separating the individual sandstone reservoirs, the slope clays and marls of the Mokrin Formation behave as a regional seal over the entire area. Investigation of a recently acquired 3D seismic cube ...
... U se a t h tt p :/ /l ib ra ry .s eg .o rg / Prosser, S., 1993, Rift related depositional system and their seismic expression, in G. D. Williams and A. Dobb, eds., Tectonics and seismic sequence stratigraphy: Geological Society of London, Special Publications, 35–66. Răbăgia, A. M., 2009 ...Saša Ivanišević, Dejan Radivojević. "Upper Miocene depositional environments of the Kikinda-Mokrin High (Serbia)" in Interpretation, AAPG SEG (2018). https://doi.org/10.1190/INT-2017-0084.1
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Lower Berriasian ammonites from Dedina (Golubac Mountains, eastern Serbia) and their biostratigraphic implication
... |_f|4 Hi LI | |}- -} -_-L}] E B I J EsH|I ||BLJ-| a -B EaE E s |M | LJ |E | J E || || || A / | | j ||> |M | || }A | | || -i I L J Lj - I - - -| | - { | LJ ||_|| |A|}_| |_{L_| |f= | L J i |Epi|s | s | | 5 / % Bie|||s|P|P{E|S| ...
... (specimen SA13.2/12). It has a heavily corroded, flatly deformed first quarter of the last whorl and part of the third quarter of the last whorl, with a more favourable preservation of a less corroded outer mould. The unfavourably pre- served opposite side shows a small segment of development ...
... transitions rather abruptly into a narrow ventral side. The whorl at the base falls off with a not-very high, but clearly defined, oblique umbilical wall. The body chamber is separated from the phrag- mocone by a distinct constriction. The juvenile sculpture changes at a diameter of approximately 22 ...Zdenek Vasícek , Dragoman Rabrenović, Petr Skupien, Barbara Radulović. "Lower Berriasian ammonites from Dedina (Golubac Mountains, eastern Serbia) and their biostratigraphic implication" in Cretaceous Research (2023). https://doi.org/10.1016/j.cretres.2023.105623
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Услови заштите изворишта подземних вода “Јарош“ за водоснабдевање Сомбора
Ивана Јовановић (2024)Територија града Сомбор се налази у периферном северозападном делу Војводине, односно Србије, у близини границе са Хрватском. Сам град Сомбор се налази југозападном делу територије и представља гравитациони центар тог подручја. Повољан географски положај условио је афирмацију Сомбора као градског насеља, са јаком пољопривредом, индустријом, занатством и прометом. "ВОДОКАНАЛ" из Сомбора је јавно комунално предузеће чија је основна делатност захват сирове подземне воде, њен третман, и дистрибуција ка потрошачима Сомбора и приградских насеља и насељених места: Лугова, Жарковца, Чонопље, ...... caJerakoen--OMŠ 9. H3BOPH IIOTEHTIHJA.THHX 3AT AĐEĐĐA H OIIEHA CTAĐA HOCTOJE TE POLITEKICA a a as a aA a a V OE OO O A 58 10. IIPE,T.TOT MEPA 3A YCIIOCTAB.bAĐĐE KOHTHHYA.IHOF MOHHTOPHHT A BO,TA Y 3OHAMA CAHHTAPHE 3AITIHTHTE _ 58 ı8B OJE 74 2 · 2225 - - OOAIAAIAJAIRAAARIAAAIJAARAAIINAAIIAAAGAAAA ...
... R KI _ i : _ – – p - P M Kl – a DD ~ [. g a ~ ~ ~ [ [. |. [. [ b b , h h h h h , h h h , h a ~ – m af ~+ [1z] :Pa] ~ [53] | y} e — a – – o [-] o o o o o [-] [>] – – _ , ' rl Y Y Y y rl r r Q , , i 5= – | – —~ e o |o} [ ) —~ yy l o o r [7 —| m m [2 a ~ a [ ra [ a Datum Cnuka 26. IIpuxas zpevaxe ...
... HeHmleMOpy H JaHyapy, a HajMažba TOKOM JIeTa Y MeCeTIyH JyJy, CTMKA 5. - O : 0 - - - B a a a g o c T Ba ya yx a (% ) -M R- U- ) – -- 0 || 2 3 d bj 6 7 8 9 IO IL 1 Cnuka 5. JTujazpau cpe0me Meceunux suuezo0utuhbux apeoOnocmu snažcHocmu 6a30VXG pezucmposaHux a YXMC Cow6op, y nepuooy ...Ивана Јовановић. Услови заштите изворишта подземних вода “Јарош“ за водоснабдевање Сомбора, 2024
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Flood protection and water utilization of karst poljes: example of Gatačko Polje, Eastern Herzegovina
Tina Dašić, Ljiljana Vasić (2020)Earth-Surface Processes,Geology, Pollution, Soil Science, Water Science and Technology, Environmental Chemistry,Global and Planetary ChangeTina Dašić, Ljiljana Vasić. "Flood protection and water utilization of karst poljes: example of Gatačko Polje, Eastern Herzegovina" in Environmental Earth Sciences, Springer Science and Business Media LLC (2020). https://doi.org/10.1007/s12665-020-08987-4
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Evaluation of the effects of wastewater heat pump integration into district heating systems by simulation
Dejan Ivezić, Marija Živković, Dimitrije Manić, Aleksandar Madžarević, Boban Pavlović, Dušan Danilović (2023)The integration of wastewater heat pumps (using purified water) in district heating systems is analyzed in this paper. The simulation procedure is proposed to analyze the impacts of stochasticity of purified water temperature and flow to heat pump integration and operation. The analysis includes calculation of the daily and seasonal coefficient of performance, as well as fossil fuel savings and CO2 emission reduction due to wastewater heat pump use. The proposed procedure is implemented for the case study in ...Dejan Ivezić, Marija Živković, Dimitrije Manić, Aleksandar Madžarević, Boban Pavlović, Dušan Danilović. "Evaluation of the effects of wastewater heat pump integration into district heating systems by simulation" in Thermal Science, National Library of Serbia (2023). https://doi.org/10.2298/TSCI220813168I
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Geotehnički uslovi izgradnje tunela „Debelo brdo“ na autoputu E-80 Niš - Pločnik
Tunel „Debelo brdo“ nazvan je po najizraženijem relјefnom obliku na ovoj drugoj deonici autoputa E-80 Niš – Pločnik. Osnovnu geološku građu na lokaciji tunela čini Mio-Plioceni kompleks heterogenog litološkog sastava. Izgradnja tunela je predviđena delom u otvorenom iskopu dužine 240 m, a delom sa podzemnim iskopom dužine 190 m. U zoni tunela, padina je okarakterisana kao uslovno stabilna, pa bi neadekvatna zasecanja mogla da izazovu klizanja terena. Iz tih razloga, u okviru rada posebno su prikazani geotehnički uslovi izgradnje ...... AUTOPUTU E- - 1, 2 3 4 1 Univerzitet u Beogradu Rudarsko- a 7, Beograd, dragoslav.rakic@rgf.bg.ac.rs 2 Univerzitet u Beogradu Rudarsko- a 7, Beograd, radojica.lapcevic@rgf.bg.ac.rs 3 Univerzitet u Beogradu Rudarsko-g a 7, Beograd, irena.basaric@rgf.bg.ac.rs 4 Univerzitet u Novom Sadu ...
... kojima se lako cepa i odvaja (Slika 3b), lokalno je masivan. -cm dimenzija. (Slika 3c), dok su u drugim a povremeno se retko javljaju i sitni , a konstatovan je na a) b) c) Slika 3. Makroskopski izgled laporovitih glina,glinovitih lapora i proslojka peska U dve e ...
... Dragoslav Radojica , Irena 40 a) b) Slika 5. dardne jednoaksijalne opite iz rezultata jednoaksijalnih opita, korelacionih zavisnosti sa rezultatima SPT opita. Nedrenirana a smicanja su za laporovite gline (gl-prL se u intervalu od Su = 121 237 kPa, a za lapore glinovite (Lgl,pr) Su ...Dragoslav Rakić, Radojica Lapčević, Irena Basarić Ikodinović, Dragan Lukić. "Geotehnički uslovi izgradnje tunela „Debelo brdo“ na autoputu E-80 Niš - Pločnik" in Četvrti Srpski kongres o putevima, 2-3. jun 2022., Beograd : Srpsko društvo za puteve Via Vita (2022)
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Refinement of waste phosphogypsum from Prahovo, Serbia: characterization and assessment of application in civil engineering
Josip Išek, Lazar Kaluđerović, Nikola Vuković, Maja Milošević, Ivana Vukašinović, Zorica Tomić (2020)... natural radioactive series for a period of 4 weeks. The activity concentra- tion of radionuclides was determined using a high-purity germa- nium radiation detector of 50% relative efficiency. The detector was calibrated using a secondary reference material with a char- coal matrix in the same 120 ...
... Accepted Manuscript online: 28 April 2020; Associate Editor: Asuman Turkmenoglu) Phosphogypsum is a waste product of the phosphoric acid manu- facturing process. It is produced in the form of a fine powder with a large calcium sulfate content. This process produces ~5 tons of phosphogypsum for every ton ...
... higher activity concentration of 2%U, was further subjected to the recrystallization process (Fig. 2). A total of 10 g of the sample was mixed with 2 L of distilled water in a beaker. Using a magnetic stirrer, the mixture was stirred for 2 h at ~45%C, allowed to settle for 2 h at the same tempera- ...Josip Išek, Lazar Kaluđerović, Nikola Vuković, Maja Milošević, Ivana Vukašinović, Zorica Tomić. "Refinement of waste phosphogypsum from Prahovo, Serbia: characterization and assessment of application in civil engineering" in Clay Minerals, Cambridge University press (2020). https://doi.org/10.1180/clm.2020.11
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Effectiveness Analysis of Different Bucket-wheel Excavators
Coal production in open-pit lignite mines in the Republic of Serbia is performed with continuous work systems. In addition to coal production, the same systems are used for the exploitation of large quantities of overburden. According to the reliability concept, continuous systems are in linear connection. If the failure occurs in one part of the system, that will produce a downtime of the entire system. The initial and most important factor of continuous systems is the bucket-wheel excavator. It ...... 1 2 2 2 21 22 2 1 2 1 2 ... ... ... ... ... ... ... ... ... ... ... ... ... ... n n n n n n n n n n nn w w w w w w a a a w w w w w w a a a M w w w w w w a a a = = (1) By calculating the matrix, the result of the AHP method was obtained ...
... 9. Bazzazi, A. A., Osanloo, M., &Karimi, B. (2011). Deriving preference order of open pit mines equipment through MADM methods: Application of modified VIKOR method. Expert Systems with Applications, 38(3), 2550-2556. 248 10. Bazzazi, A. A., Osanloo, M., &Karimi, B. (2011). A new Fuzzy multi ...
... matrix with applying the equation (9) and (10) values of ideal (A+) and anti- ideal (A-) solution. By using equations (11) and (12) the distance of each alternative from the ideal solution (Si +, Si) is calculated. The values of (A+) and (A-) are presented in Table 8, and in Table 9 are values of (Si ...Stevan Đenadić, Predrag Jovančić, Dragan Ignjatović, Miloš Tanasijević, Filip Miletić. "Effectiveness Analysis of Different Bucket-wheel Excavators" in 8th International Conference Mining and Environmental Protection, Sokobanja, 22-25 September 2021, University of Belgrade, Faculty of Mining and Geology, Belgrade, Serbia (2021)
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The Fuzzy–AHP Synthesis Model for Energy Security Assessment of the Serbian Natural Gas Sector
Natural gas is used for the production of almost 20% of total energy today. The natural gas security of the Republic of Serbia is an urgent strategic, political and security issue. Serbia is one of the most vulnerable countries in Southeast Europe, because it only has one supply route. This study is a contribution to efforts to better understand the factors affecting energy security through the implementation of a new methodology based on the fuzzy–AHP synthesis model for measuring ...Aleksandar R. Madžarević, Dejan D. Ivezić, Miloš L. Tanasijević, Marija A. Živković. "The Fuzzy–AHP Synthesis Model for Energy Security Assessment of the Serbian Natural Gas Sector" in Symmetry, MDPI AG (2020). https://doi.org/10.3390/sym12060908